Open source infrastructure has paved the way for mission-aligned research stakeholders to create a united vision of interoperable tools and services that accelerate scholarly communication, fill technology gaps, converge solutions, and enable access …
Background: We explore whether the number of null results in large National Heart Lung, and Blood Institute (NHLBI) funded trials has increased over time. Methods: We identified all large NHLBI supported RCTs between 1970 and 2012 evaluating drugs or …
This recorded webinar features insights from international panelists currently nurturing culture change in research among their local communities.Representat...
Genetics and neuroscience are two areas of science that pose particular methodological problems because they involve detecting weak signals (i.e., small effects) in noisy data. In recent years, increasing numbers of studies have attempted to bridge …
The vast majority of health-related observational studies are not prospectively registered and the advantages of registration have not been fully appreciated. Nonetheless, international standards require approval of study protocols by an independent …
Many philosophers of science and methodologists have argued that the ability to repeat studies and obtain similar results is an essential component of science. A finding is elevated from single observation to scientific evidence when the procedures …
Science journalists are uniquely positioned to increase the societal impact of open science by contextualizing and communicating research findings in ways that highlight their relevance and implications for non-specialist audiences. Through …
The university participant pool is a key resource for behavioral research, and data quality is believed to vary over the course of the academic semester. This crowdsourced project examined time of semester variation in 10 known effects, 10 individual …
Cases of clear scientific misconduct have received significant media attention recently, but less flagrantly questionable research practices may be more prevalent and, ultimately, more damaging to the academic enterprise. Using an anonymous …