Background*: Nat Goodman is generally pessimistic about the benefits of pre-registration. Bob Reed is generally optimistic about pre-registration. What follows is a back-and-forth dialogue about what each likes and dislikes about pre-registration.* [GOODMAN, Opening Statement] We need to remember that science is a contradictory gimish of activities: creative and mundane; fuelled by curiosity and dogged by methodological minutia; fascinating and boring; rigorous and intuitive; exploratory, iterative, incremental, and definitive.